Perbedaan kadar kalsium serum antara pasien geriatri PPOK dan asma di RSUD dr. Moewardi Surakarta

Oleh :
Sartika Sari - G0006153 -

ABSTRAK Tujuan Penelitian: Seiring dengan meningkatnya penderita PPOK dan asma, banyak peneliti yang menduga adanya hubungan antara PPOK dan asma dengan kadar kalsium serum dimana terjadi penurunan kadar kalsium serum. Penurunan kadar kalsium ini merupakan proses awal dari demineralisasi tulang berlebihan yang dapat mengakibatkan tulang menjadi keropos (osteoporosis). Namun apakah ada perbedaan kadar penurunan kalsium serum di antara PPOK dan asma masih belum diketahui. Penelitian ini betujuan untuk melihat apakah ada perbedaan kadar kalsium serum antara pasien geriatri PPOK dan asma. Metode Penelitian: Penelitian analitik observasional dengan pendekatan Cross Sectional. Subjek penelitian pasien geriatri PPOK dan asma di RSUD Dr. Moewardi. Besar sampel sebanyak 30 pasien dengan menggunakan tehnik consecutive (quota) sampling, dimana terdiri dari 15 pasien geriatri PPOK dan 15 pasien geriatri asma. Setiap sampel diukur kadar kalsium serum nya, kemudian dianalisis dengan uji t Independent. Hasil Penelitian: Hasil uji T Independent didapatkan nilai sig 0.005 atau probabilitas di bawah 0.05 ( p < 0.05). Sehingga H0 ditolak, atau kadar kalsium pasien geriatri PPOK berbeda dengan kadar kasium pasien geriatri asma Simpulan Penelitian: Terdapat perbedaan kadar kalsium serum yang bermakna antara pasien geriatri PPOK dan asma, dimana pada pasien geriatri PPOK didapatkan kadar kalsium yang lebih rendah dibandingkan dengan kadar kalsium serum pasien geriatri asma. Kadar kalsium yang rendah merupakan tanda awal dari osteoporosis. ABSTRACT Objective: Together with increasing interest in patient with COPD and asthma, many researchers presume there is correlation between COPD and asthma with serum calcium concentrations which occur decreasing of serum calcium concentrations. Low serum calcium concentrations is begining process of bone demineralization that can cause bone loss. However, whether there are differences of serum calcium concentrations between COPD and asthma are not yet known. This research purpose to show whether there is differences of serum calcium concentrations between COPD and asthma. Methods: Observational analytic research by using cross sectional. The subjects are geriatric COPD patients and asthma in RSUD Dr. Moewardi. Samples size are 30 patients with consecutive (quota) sampling used, consist of 15 geriatric COPD patients and 15 geriatric asthma patients. Their serum calcium concentrations is measured and then analysed with difference two average test (Independent sample t test). Results: The result of independent t test is known that sig. 0.005 or probability under 0.05 ( p < 0.05). With the result that H0 is refused or serum calcium concentrations in geriatric COPD patients different with serum calcium concentrations in geriatric asthma patients. Conclusion: There is significant differences of serum calcium concentrations between geriatric COPD patients and ashma which in geriatric COPD patients concentration of serum calcium is lower than geriatric asthma patients. Low serum calcium concentrations is marker for osteoporosis.