Pembuatan Salep Minyak Atsiri Daun Jeruk Limau (Citrus Amblycarpa (Hassk) Ochse) dan Uji Stabilitas terhadap Tipe Basis yang digunakan

Oleh :
Nindya Nareswari - M3508053 - Fak. MIPA

Citrus lime has a content of volatile oil contained in the leaves and the skin. Essential oils from the leaves of citrus lime-containing β-pinena, linalool, citronellal, and geraniol sitronelol. The yield of essential oil of citrus lime leaves 0,47% could inhibit the growth of bacteria S.aureus with KBM and the MIC values of 0,039% (v / v). This research is desain experimental that used Pre Test Post Test Control Desain. The essential oil for skin medication has to be made in practical and stable preparation. Ointment is a semi solid preparation which is easy to be applied and to be used as the external medicine.The use of essential oil of citrus lime leaf was made in ointment preparation with three varieties of basis, those are water-soluble basis, absorptive bases and base hidokarbon, in order for the ointment to be easily applied into skin . The physical stability test series which consisted of the homegeneity, the organoleptic, the viscosity the adhesiveness, and the dispersiveness and the acidity level (pH) of the oinment preparation was tested for 8 weeks in order to investigate the most stable ointment basis out of the three formulae to make the ointment of the essential oil of citrus lime (Citrus amblycarpa (Hassk) ochse). Next, the stability of the ointment preparations was investigated from the data which contained the results of the observation from the first week to the eighth week. The data were analyzed statistically by using the Kolmogorov-Smirnovanalysis technique. Finally, the data were analyzed by using the one-way Analysis of Variance (ANOVA) in order to investigate the effect of the difference in the basis of the ointment on the stability of the ointment preparations. The results of the research indicate that all three types of base oils used in ointment citrus lime leaves have a good physical stability test based on the results of the viscosity, the acidity level (pH), the dispersiveness and the adhesiveness. Keywords: Essential oils, Citrus amblycarpa (Hassk) ochse, type of ointment base, ointment stability.