Parity and Early Menarche as a Risk Factor
for Breast Cancer Positif Hormon Reseptor in
Solo female population
Kresna A1, K
Yarso2
1Resident general medical faculty Sebelas Maret University, Solo, Indon
esia; 2Sub devisi
o
n
Oncologic Surgery, Surgery Depart
ement medical faculty Sebelas Maret, Solo, Indonesia
Introduction : Recent studies
of epidemiology show that difference of hormone receptor
status
gives differences of clinical and etiologi description. Ag
e at menarche, Body Mass Index (BMI),
parity, age a
t first child birth, and history of oral contraceptives use have been suggested
affecting hormone recepto status.
Methods :
Case
-
control study was conducted to breast cancer patients in 2016 at Dr. Moewardi
Hospital Solo, there were
154 patients selected,
consisted of 74 breast cancer patients with
positive hormone receptor (HR+) as group of cases
and 80 breast cancer patients with negative
hormone receptor (HR as group of control).
Results : Early age at menarches (12 years) (OR=3.590, P=0.002) and nulipar
a
or primipara (OR
4.059; P 0.001) were
significant risk factor for hormone receptor positive (HR+) in breast cancer
patients. Early menarches (12 years) and nulipara or primipara ware proved as a risk factor for
hormone receptor positive (HR+) in breast c
ancer patients in Solo female population
.
