Abstract: Background: Nipple-sparing mastectomies (NSMs) are a relatively newmethod of conservatism in the treatment of breast cancer. Most of the breast skin is leftintact during NSM, creating a pocket that can be filled with an implant or anautologous graft for a rapid reconstruction that yields an excellent cosmetic outcome.Combining prosthetic-based breast restoration with autologous flaps, such thelatissimus dorsi (LD) flap, may be necessary to achieve symmetry. Case Description :A 45 year old woman who developed a breast deformity following a mastectomy forbreast cancer. The Latissimus dorsi (LD) flap was chosen because it is a thin layer flapwith good vascularization. The Latissimus dorsi (LD) flap, on the other hand,necessitates a different skin incision than the mastectomy. An inframammaryadipofascial flap has been used as an autologous flap in conjunction with prostheticbasedbreast reconstruction subsequent to nipple-sparing mastectomy (NSM). In thisinstance, the Latissimus dorsi muscle flap was employed in the axillary and breastregions. The Latissimus dorsi (LD) flap was deemed suitable as it can provideextensive coverage without any delay in the transfer procedure. Anatomically, this flapand its vascular supply are quite consistent. The arterial supply is provided by thethoraco-dorsal artery which provides a large branch to the serratus anterior muscle andprovides a cutaneous branch. Successful management of the infection, postoperativepartial weight bearing, and restricted range of motion in the affected breast wasanticipated. Conclusion: The latissimus dorsi flap is a safe choice for skin regenerationafter a nipple sparing mastectomy. This procedure has the advantage of minimizingdonor site morbidity.