Evaluasi Radiologi Menggunakan Skor Radiograpich Union Scale In Tibial (RUST) Pada Proses Penyembuhan Fraktur Yang Mengalami Perlakuan Mekanik Dengan Periosteal Stripping Dan Non Periosteal Stripping Tulang Pada TIkus Sprague Dawley

Penulis Utama : Septriarta P
NIM / NIP : S562002005
× <p class="MsoNormal" xss=removed><b><span xss=removed>Background: </span></b><span xss=removed>Periosteal stripping (PS) is a controversial technique in fracture<span xss=removed> </span></span><span xss=removed>management, with studies reporting both positive and negative effects on<span xss=removed> </span>bone healing. This study aims to evaluate the effectiveness of PS and non-<span xss=removed> </span>periosteal stripping (NPS) on fracture healing in the Sprague Dawley rat<span xss=removed> </span>model.<span xss=removed> </span><b>Methods:<span xss=removed> </span></b>This<span xss=removed> </span>study<span xss=removed> </span>is<span xss=removed> </span>an<span xss=removed> </span>in<span xss=removed> </span>vivo<span xss=removed> </span>experimental<span xss=removed> </span>research.<span xss=removed> </span>Male<span xss=removed> </span>Sprague Dawley rats (8-10 weeks old) were divided into four groups (n=10<span xss=removed> </span>per<span xss=removed> </span>group): Group I: NPS, evaluation day 14; Group  II: PS, evaluation day<span xss=removed> </span>14;<span xss=removed> </span>Group<span xss=removed> </span>III:<span xss=removed> </span>NPS,<span xss=removed> </span>evaluation<span xss=removed> </span>day<span xss=removed> </span>28<span xss=removed> </span>and<span xss=removed> </span>Group<span xss=removed> </span>IV:<span xss=removed> </span>PS,<span xss=removed> </span>evaluation<span xss=removed> </span>day<span xss=removed> </span>28.<span xss=removed> </span>A standard fracture was created in the tibia, and PS or NPS was performed.<span xss=removed> </span>Radiographic evaluation was performed on days 14 and 28, with the RUST<span xss=removed> </span>score (Radiographic Union Score for Tibia) used to assess fracture healing.<span xss=removed> </span>Statistical analysis was performed using the Kruskal-Wallis test. <b>Results:<span xss=removed> </span></b>The RUST score showed better fracture healing in the NPS group compared<span xss=removed> </span>to PS on day 28 (p<0 xss=removed> </span>(p>0.05).<span xss=removed> </span><b>Conclusion:<span xss=removed> </span></b>NPS<span xss=removed> </span>was<span xss=removed> </span>more<span xss=removed> </span>effective<span xss=removed> </span>in<span xss=removed> </span>accelerating<span xss=removed> </span>fracture<span xss=removed> </span>healing in Sprague Dawley rats than PS, especially in the later stages of<span xss=removed> </span>healing. These findings provide further evidence of the potential adverse<span xss=removed> </span>effects of PS and highlight the importance of considering time in assessing<span xss=removed> </span>its<span xss=removed> </span>efficacy.</span><span xss=removed><o></o></span></p>