Hubungan Derajat Aktivitas Lupus Eritematosus Sistemik (LES) 

dengan Anemia pada Anak 

Rifah Rosyidah, Ganung Harsono, Husnia Auliyatul Umma

Bagian Ilmu Kesehatan Anak Fakultas Kedokteran Universitas Sebelas Maret/RSUD Dr. Moewardi, Surakarta

Latar belakang. Pasien LES anak sering menunjukkan manifestasi hematologis seperti anemia, trombositopenia, dan leukopenia. Sekitar 50% pasien dengan LES mengalami anemia.

Tujuan. Menganalisis hubungan antara derajat aktivitas penyakit LES dengan anemia pada anak.

Metode. Penelitian potong lintang dilakukan pada 44 anak berusia 1 bulan-18 tahun dengan diagnosis LES di poliklinik anak RSUD Dr. Moewardi pada bulan Juli 2024-November 2024. Analisis menggunakan SPSS 25. Nilai p<0>

Hasil. Sebagian besar pasien berjenis kelamin perempuan (86.4%) dengan usia rata-rata 14 tahun. Status gizi masuk kategori normal (63.6%), dan lama sakit sebagian besar <5 OR=9.41; p=0.031) OR=4.42; p=0.048) OR=14.73; p=0.019)>

Kesimpulan. Status gizi dan Derajat aktivitas penyakit berpengaruh signifikan dengan kejadian anemia pada anak. 

Kata kunci: Derajat aktivitas penyakit, LES anak, SLEDAI.

Relationship between Degree of Systemic Lupus Erythematosus (SLE) Activity and Anemia in Children 

Rifah Rosyidah, Ganung Harsono, Husnia Auliyatul Umma

Department of Child Health, Faculty of Medicine, Sebelas Maret University/Dr. Moewardi Hospital, Surakarta

Background. Children with SLE often show hematological manifestations such as anemia, thrombocytopenia, and leukopenia. Approximately 50% of SLE patients experience anemia.

Objective. To analyze the relationship between the degree of SLE disease activity and anemia in children.

Methods. A cross-sectional study was conducted on 44 children aged 1 month to 18 years diagnosed with SLE at the pediatric outpatient clinic of Dr. Moewardi Hospital from July 2024 to December 2024. Data were analyzed using SPSS 25. A p-value <0>

Result Most patients were female (86.4%) with a median age of 14 years. The majority had normal nutritional status (63.6%), and most had a disease duration of <5 OR=9.41; p=0.031) OR=4.42; p=0.048) OR=14.73; p=0.019)>

Conclusion. Nutritional status and the degree of disease activity significantly influence the incidence of anemia in children with SLE.

Keywords:  Disease activity degree, pediatric SLE, SLEDAI