Parity and Early Menarche as a Risk Factor

for Breast Cancer Positif Hormon Reseptor in

Solo female population

Kresna A1, K

Yarso2

1Resident general medical faculty Sebelas Maret University, Solo, Indon

esia; 2Sub devisi

o

n

Oncologic Surgery, Surgery Depart

ement medical faculty Sebelas Maret, Solo, Indonesia

Introduction : Recent studies

of epidemiology show that difference of hormone receptor

status

gives differences of clinical and etiologi description. Ag

e at menarche, Body Mass Index (BMI),

parity, age a

t first child birth, and history of oral contraceptives use have been suggested

affecting hormone recepto status.

Methods :

Case

-

control study was conducted to breast cancer patients in 2016 at Dr. Moewardi

Hospital Solo, there were

154 patients selected,

consisted of 74 breast cancer patients with

positive hormone receptor (HR+) as group of cases

and 80 breast cancer patients with negative

hormone receptor (HR as group of control).

Results : Early age at menarches (12 years) (OR=3.590, P=0.002) and nulipar

a

or primipara (OR

4.059; P 0.001) were

significant risk factor for hormone receptor positive (HR+) in breast cancer

patients. Early menarches (12 years) and nulipara or primipara ware proved as a risk factor for

hormone receptor positive (HR+) in breast c

ancer patients in Solo female population

.