Penulis Utama : Samuel
NIM / NIP : S601408006

This was a pre and post test group clinical trials held in pulmonology outpatient clinic in Dr. Moewardi general hospital Surakarta from January to February 2018 using purposive sampling. The COPD group C and D patients were cathegorized as intervention group which received allopurinol 300 mg/day for 4 weeks and control group which did not receive allopurinol. Glutathione sulfhydryl serum level, %VEP1, 6MWT, and CAT score were measured at baseline and after 4 weeks in both groups.
Results: A total of 37 stable COPD group C and D patients were included in this study. The intervention group showed decreased of GSH level (52.58 ± 38.39) µg/ml and CAT score (10.37 ± 4.46) which were statistically significant compared to control group (p<0 p=0.94). p=0.005) p=0.109) p=0.057.  >Conclusion: Allopurinol decreased GSH serum level, didn’t influence %VEP1, increased 6MWT, and decreased CAT score of stable COPD group C and D patients.
Keywords: COPD,  allopurinol, GSH, %VEP1, 6MWT, CAT

Penulis Utama : Samuel
Penulis Tambahan : -
NIM / NIP : S601408006
Tahun : 2018
Judul : Pengaruh allopurinol terhadap kadar glutathione sulfhydryl (GSH), nilai %vep1, six minute walking test, dan skor cat pasien penyakit paru obstruktif kronik (PPOK) stabil
Edisi :
Imprint : Surakarta - F. Kedokteran - 2018
Program Studi : PPDS Pulmonologi
Kolasi :
Sumber : UNS-F. Kedokteran Prog Studi Pulmonologi dan Kedokteran Repirasi-S601408006-2018
Kata Kunci :
Jenis Dokumen : Tesis
Link DOI / Jurnal : -
Status : Public
Pembimbing : 1. Prof. DR. Suradi, Dr., Sp.P(K), MARS, FISR
2. DR., Yusup Subagio Sutanto, Dr., Sp.P(K), FISR
Penguji :
Catatan Umum :
Fakultas : Fak. Kedokteran
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