| Penulis Utama | : | Iqbal Maulana Malik |
| NIM / NIP | : | S592108003 |
Background and Aim
Early-onset neonatal sepsis (EONS) remains a challenging problem in preterm infants, as it presents with nonspecific clinical signs and requires time-consuming tests for definitive diagnosis. The neutrophil-lymphocyte ratio (NLR) and platelet-lymphocyte ratio (PLR) are potential early markers that are simple, affordable, and routinely available. This study aimed to compare NLR and PLR as early markers of EONS in preterm infants.
Materials and Methods
This observational cross-sectional study was conducted at Dr. Moewardi General Hospital, Surakarta, from August 2024 to January 2025. The study involved preterm infants aged ≤72 hours suspected of having sepsis. NLR and PLR values were analyzed using receiver operating characteristic (ROC) curves to determine sensitivity, specificity, and cut-off points.
Results
A total of 50 subjects were included, with 33 infants having EONS. NLR and PLR were significantly higher in the EONS group (p < 0 xss=removed xss=removed xss=removed xss=removed>
Conclusion
NLR and PLR are reliable early markers for EONS in preterm infants, with improved diagnostic accuracy when used in combination, especially in resource-limited settings.
| Penulis Utama | : | Iqbal Maulana Malik |
| Penulis Tambahan | : | - |
| NIM / NIP | : | S592108003 |
| Tahun | : | 2025 |
| Judul | : | Rasio Neutrofil-Limfosit dan Rasio Platelet-Limfosit Sebagai Penanda Awal Sepsis Neonatorum Awitan Dini pada Bayi Kurang Bulan |
| Edisi | : | |
| Imprint | : | Surakarta - Fak. Kedokteran - 2025 |
| Program Studi | : | PPDS Ilmu Kesehatan Anak |
| Kolasi | : | |
| Sumber | : | |
| Kata Kunci | : | Neonatal sepsis, early-onset neonatal sepsis, preterm infants, neutrophil-lymphocyte ratio, platelet-lymphocyte ratio, biomarkers |
| Jenis Dokumen | : | Tesis |
| ISSN | : | |
| ISBN | : | |
| Link DOI / Jurnal | : | - |
| Link DOI | : | - |
| Status | : | Public |
| Pembimbing | : |
1. Dr. dr. Dwi Hidayah, Sp.A, Subsp.Neo(K), M.Kes 2. Dr. dr. Muhammad Riza, Sp.A, Subsp.HO(K), M.Kes |
| Penguji | : |
1. dr. H. Rustam Siregar, Sp.A 2. Dr. dr. Fadhilah Tia Nur, Sp.A, Subsp.Neuro(K), M.Kes |
| Catatan Umum | : | |
| Fakultas | : | Fak. Kedokteran |
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